Our research is conducted both in basic science and patient-oriented research. Basic research is centered on renal physiology, metabolism, and epithelial biology. Patient-oriented research is focused on the pathophysiology of nephrolithiasis. We strive to cross from the level of the whole patient, to animal and cell culture models, and down to single molecules.
RESEARCH INTERESTS
Epithelial Biology
Ion Transport
Metabolism
RECENT PUBLICATIONS
Moe OW, "PiT-2 Coming out of the Pits" Am J Physiol Renal Physiol, 296:F689-90, April 2009
Reining SC, Gisler SM, Fuster D, Moe OW, O?Sullivan GA, Betz H, Biber J, Murer H, Hernando N, "GABARAP deficiency modulates the expression of NaPi-IIa in renal brush border membranes" Am J Physiol Renal Physiol, 296:F1118-F1128, February 2009
Bobulescu IA, Moe OW, "Luminal Na(+)/H (+) exchange in the proximal tubule" Pflugers Arch, 458:5-21, October 2009
Sas D, Hu M, Moe OW, Baum M, "Effect of claudins 6 and 9 on paracellular permeability in MDCK II cells" Am J Physiol Regul Integr Comp Physiol, 295:R1713-9, November 2008
Geng W, Hill K, Zerwekh J, Kohler T, Muller R, Moe O, "Inhibition of osteoclast formation and function by bicarbonate: role of soluble adenylyl cyclase" J Cellular Phys, Epub:online, April 2009
SIGNIFICANT PUBLICATIONS
Bonny O, Rubin A, Huang C-L, Frawley WH, Pak CYC, Moe OW, "Mechanism of urinary calcium regulation by urinary magnesium and pH" J Am Soc Nephrology, Epub ahead of print April 2008
Pak CY, Moe OW, Maalouf N, Zerwekh JE, Poindexter JR, Adams-Huet B, Rodgers K., "Comparison of semi-empirical and computer derived methods for estimating urinary saturation of brushite" J Urol, 181:1423-8, March 2009
Fuster D, Moe OW, Hilgemann DW, "Steady-state function of the ubiquitous mammalian Na/H exchanger (NHE1) in relation to dimer coupling models with 2Na/2H stoichiometry" J Gen Physiol, 132:465-80, October 2008
Zhang Q, Zhang J, Moe OW, Hsia CC, "Synergistic upregulation of erythropoietin receptor (EPO-R) expression by sense and antisense EPO-R transcripts in the canine lung" Proc Natl Acad Sci USA, 105:7612-7617, May 2008
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