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Orson Moe

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Orson Moe, M.D.

Details of Research

Name:		Orson Willy Moe, M.D.
Endowed Title:		Donald W. Seldin Professorship in Clinical Investigation The Charles Pak Distinguished Chair in Mineral Metabolism
Academic Title:		Professor
Primary Appointment:		Internal Medicine - Nephrology
Secondary Appointment:		Center for Mineral Metabolism and Clinical Research
School:		Graduate School of Biomedical Sciences Southwestern Medical School
Degree Program:		Integrative Biology
Non-degree Program:		STARS
Affiliations:		Hayes Center for Mineral Metabolism Internal Medicine
Department Website:		Charles and Jane Pak Center for Mineral Metabolism and Clinical Research
Email:		Orson Moe, M.D.

RESEARCH INTERESTS

	Epithelial Biology
	Ion Transport
	Metabolism

RECENT PUBLICATIONS

	Bobulescu IA, Dwarakanath V, Zhang J, Baum M, Moe OW, "Glucocorticoid acutely increases cell surface Na+/H+ exchanger-3 (NHE3) by activation of NHE3 exocytosis" Am J Physiol Renal Physiol, 289:F685-F691, 2005
	Kurosu H, Ogawa Y, Miyoshi M, Yamamoto M, Nandi A, Rosenblatt KP, Baum MG, Schiavi S, Hu MC, Moe OW, Kuro-o M, "Regulation of fibroblast growth factor-23 signaling by klotho" J Biol Chem, 281:6120-6123, 2006
	Fuster DG, Bobulescu IA, Zhang J, Wade J, Moe OW, "Characterization of the regulation of renal Na+/H+ exchanger NHE3 by insulin" Am J Physiol Renal Physiol, 292:F577-585, 2007
	Wang D, Hu J, Bobulescu IA, Quill TA, McLeroy P, Moe OW, Garbers DL, "A sperm-specific Na+/H+ exchanger (sNHE) is critical for soluble adenylyl cyclase (sAC) expression and regulation by bicarbonate" Proc Natl Acad Sci USA, 104:9325-9230, 2007
	Jianning Z, Bobulescu IA, Goyal S, Aronson PS, Baum MG, Moe OW, "Characterization of Na+/H+ exchanger NHE8 in cultured renal epithelial cells" Am J Physiol Renal Physiol, In press. 2007

SIGNIFICANT PUBLICATIONS

	Bobulescu A, Di Sole F, Moe OW, "Na+/H+ exchangers: Physiology and link to hypertension and organ ischemia" Curr Opin Nephrol Hypertens, 14:485-494, 2005
	Moe OW, "Nephrolithiasis: Pathophysiology and treatment" Lancet, 367:333-44, 2006
	Moe OW, Preisig PA, "Dual role of citrate in urine. (Editorial)" Curr Opin Nephrology Hyperten, 15:419-424, 2006
	Moe OW, "Uric acid nephrolithiasis: Protonation of an essential molecule?" Curr Opin Nephrology Hyperten, 15:366-373, 2006
	Bobulescu IA, Moe OW, "Na/H exchanges in acid-base physiology" Semin Nephrol, 26:334-344, 2006

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