Clinical applications of immunohistochemistry and in-situ hybridization
Pathology of pediatric brain tumors
Pathology of pediatric lung disease
RECENT PUBLICATIONS
Bowers DC, Mulne AF, Weprin B, Bruce DA, Shapiro K, Margraf LR., "Prognostic Factors in children and adolescents with low-grade oligodendrogliomas." J Pediatr Neurosurg, 37 (2):57-63, 2002
Bowers DC, Gargan L, Kapur P, Reish JS, Mulne AF, Shapiro KN, Elterman RD, Winick NJ, Margraf LR., "Study of the MIB-1 labeling index as a predictor of tumor progression in pilocytic astrocytomas in children and adolescents." J Clin Oncolo, 21 (15):2968-2973, 2003
Rakheja D, Margraf LR, Tomlinson GE, Schneider NR., "Hepatic mesenchymal hamartoma with translocation involving chromosomal band 19q13.4: recurrent change." Cancer Genet Cytogenet, 153 (1):60-63, 2004
Rakheja D, Lian F, Tomlinson GE, Ewalt DH, Schultz RA, Margraf LR., "Renal metanephric adenoma with previously unreported cytogenetic abnormalities: a case report and review of literature." Pediatr Dev Pathol, 8 (2):218-223, 2005
Rakheja D, Kapur P, Tomlinson GE, Margraf LR., "Pediatric renal cell carcinomas with Xp11.2 rearrangements are immunoreactive for hMLH1 and hMSH2 proteins." Pediatr Dev Pathol, 8 (6):615-620, 2006
SIGNIFICANT PUBLICATIONS
Chen J, Willingham T, Margraf LR, Schreiber-Agus N, DePinho RA, Nisen PD., "Effects of the myc oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenotype of human brain tumor cells" Nature Medicine, 1:638-643, July 1995
Margraf LR, Boriack RL, Routheut AJ, Cuppen I, Alhilali L, Bennett C, Bennett MJ., "Tissue Expression and Subcellular localization of CLN3, the Batten disease protein." Molecular Genetics and Metabolism, 66:283-289, 1999
Margraf L, Tomashefski J, Bruce M, Dahms B, "Morphometric Analysis of the Lung in Bronchopulmonary Dysplasia." American Review of Respiratory Disease, 143:391-400, 1991
Margraf LR, Finegold MJ, Stanley LA, Majors A, Hawkins HK, DeMayo FJ., "Cloning and tissue specific expression of the mouse Clara cell 10 kD gene; Comparison of endogenous expression to rabbit uteroglobin promoter driven transgene expression" Journal of Respiratory Cell and Molecular Biology, 9:231-238, March 1993
Shaul PW, North AJ, Wu LC, Wells LB, Brannon TS, Lau KS, Michel T, Margraf LR, Star RA., "Endothelial nitric oxide synthase is expressed in cultured human bronchiolar epithelium" J Clin Invest, 94:2231-2236, 1994
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