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Jennifer Cuthbert

 
 
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Jennifer Cuthbert, M.D.

 Details of Research

Biographical Sketch Details of Research Personal Overview How to Contact
Jennifer Cuthbert
Name:
  Jennifer Anne Cuthbert, M.D.
Academic Title:
  Professor
Primary Appointment:
  Internal Medicine - Digestive and Liver Diseases
School:
  Southwestern Medical School
Department Website:
  Internal Medicine - Digestive and Liver Diseases
Email:
  Jennifer Cuthbert, M.D.

 RESEARCH INTERESTS
 
Web Curriculum http://medschool.swmed.edu
Medical education
Ascites and complications of liver disease
Jaundice and acute hepatitis
 
 RECENT PUBLICATIONS
 
Cuthbert JA, "Hepatitis A: Ancient disease, emerging threat? A modern review with historical emphasis" Clin Microbiol Rev, 14:38-58, 2001
Makar RSJ, PE Lipsky and JA Cuthbert, "Multiple mechanisms, independent of sterol regulatory element binding proteins, can control low density lipoprotein gene transcription" J Lipid Res, 41:762-774, 2000
Cuthbert JA, "Wilson's disease: Update on a systemic disorder with protean manifestations." Gastroenterol Clin North Am, 27:655-682, 1998
Makar RSJ, PE Lipsky and JA Cuthbert, "Sterol-independent, sterol response element-dependent regulation of low density lipoprotein receptor gene expression" J Lipid Res, 39:1647-1654, 1998
Spady DK, JA Cuthbert, MN Willard and RS Meidell, "Overexpression of cholesterol 7alpha-hydroxylase (CYP7A) in mice lacking the low density lipoprotein (LDL) receptor gene. LDL transport and plasma LDL concentrations are reduced." J Biol Chem, 273:126-132, 1998
 
 SIGNIFICANT PUBLICATIONS
 
Cuthbert JA, CA East, DW Bilheimer and PE Lipsky, "Detection of familial hypercholesterolemia by assaying functional low-density-lipoprotein receptors on lymphocytes" N Engl J Med, 314:879-883, 1986
Cuthbert JA, DW Russell and PE Lipsky, "Regulation of low density lipoprotein receptor gene expression in human lymphocytes" J Biol Chem, 264:1298-1304, 1989
Cuthbert JA and PE Lipsky, "Inhibition by 6-fluoromevalonate demonstrates that mevalonate or one of the mevalonate phosphates is necessary for lymphocyte proliferation" J Biol Chem, 265:18568-18575, 1990
Cuthbert JA and PE Lipsky, "Negative regulation of cell proliferation by mevalonate or one of the mevalonate phosphates" J Biol Chem, 266:17966-17971, 1991
Spady DK and JA Cuthbert, "Regulation of hepatic sterol metabolism in the rat: Parallel regulation of activity and mRNA for 7alpha-hydroxylase but not 3-hydroxy-3-methylglutaryl coenzyme A reductase or low density lipoprotein receptor" J Biol Chem, 267:5584-5591, 1992
 
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