Prevention and treatment of vaso-occlusive complications of sickle cell disease during infancy, childhood, and adolescence
Better understanding of the management and natural history of idiopathic thrombocytopenic purpura during childhood, with particular emphasis on outcome measures other than platelet count (e.g., bleeding signs and symptoms, cost of therapy, and quality of life)
Development of improved means of diagnosing and treating patients with hemophilia and other hereditary blood coagulation disorders, with special emphasis on eliminating the complications of the disease and its therapy
Study of the epidemiology and pathophysiology of childhood anemias, including iron deficiency anemia and Diamond-Blackfan syndrome
Understanding the risk of thrombosis following splenectomy
RECENT PUBLICATIONS
Fu T, Corrigan NJ, Quinn CT, Rogers ZR, Buchanan GR, "Minor elective surgical procedures using general anesthesia in children with sickle cell anemia without pre-operative blood transfusions" Pediatr Blood Cancer, 45:43-47, 2005
Bennett CM, Rogers ZR, Kinnamon DD, Bussell JB, Mahoney DH, Abshire TC, Sawaf h, Moore TB, Loh ML, Glader BE, McCarthy MC, Mueller BU, Olson TA, Lorenzana AN, Mentzer WC, Buchanan GR, Feldman HA, Neufeld EJ, "Prospective phase I/II study of rituximab in childhood and adolescent chronic immune thrombocytopenic purpura" Blood, 107:2639-2642, 2006
Journeycake JM, Eshelman D, Buchanan GR, "Post-thrombotic syndrome is uncommon in childhood cancer survivors" J Pediatr, 148:275-277, 2006
Sadler ES, Homans A, Mandell L, Amylon M, Wall DA, Devidas M, Buchanan GR, Lipton JM, Billett AL, "Hematopoietic stem cell transplantation after first marrow relapse of non-T, non-B acute lymphoblastic leukemia" J Pediatr Hematol Oncol, 28:210-215, 2006
Imbach P, Kűhne T, Műller D, Berchtold W, Zimmerman S, Elalfy M, Buchanan GR, "12 months follow-up data from the prospective registry I of the Intercontinental Childhood ITP Study Group (ICIS)" Pediatr Blood Cancer, 46:351-356, 2006
SIGNIFICANT PUBLICATIONS
Glaser DW, Medeiros D, Rollins N, Buchanan GR, "Catheter-related thrombosis in children with cancer" J Pediatr, 138:255-259, 2001
Journeycake JM, Quinn CT, Miller K, Zajac J, Buchanan GR, "Catheter-related deep venous thrombosis in children with hemophilia" Blood, 98:1727-1731, 2001
Buchanan GR, Adix L, "Grading of hemorrhage in children with idiopathic thrombocytopenic purpura" J Pediatr, 141:683-688, 2002
Quinn CT, Rogers ZR, Buchanan GR, "Survival of chlidren with sickle cell disease" Blood, 103:4023-4027, 2004
Sung L, Nathan PC, Lange B, Beyene J, Buchanan GR, "Prophylactic granulocyte colony-stimulatng factor and granulocyte-marcophage colony-stimulating factor decrease febrile neutropenia after chemotherapy in children with cancer: A meta-analysis of randomized controlled trials" J Clin Oncol, 22:3350-3356, 2004
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