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NAME: Victor Ghetie
POSITION TITLE: Professor
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION DEGREE
(if applicable) YEAR(s) FIELD OF STUDY
University of Cluj, Romania B.S.. 1953 Chemistry
University of Bucharest, Romania M.S. 1955 Biochemistry
University of Bucharest, Romania Ph.D. 1959 Biochemistry
University of Bucharest, Romania D. Sc. 1971
A. Positions and Honors. List in chronological order previous positions, concluding with your present position. List any honors. Include present membership on any Federal Government public advisory committee.
PROFESSIONAL EXPERIENCE:
1971 1979 Head of the Department of Immunology, Babes Institute, Bucharest
1979 1986 Senior Scientist, Department of Immunology, Babes Institute, Bucharest
1986 1989 Associate Professor, Cancer Immunobiology Center, U.T. Southwestern Medical Center
1999 Present Professor, Cancer Immunobiology Center, U.T. Southwestern Medical Center
PROFESSIONAL COMMITTEES:
Chairman, Protein Evolution of Mendel Symposium of Mutational Processes, Prague, 1966; Co-Chairman, Swedish-Romanian Symposium on Protein Separation, Bucharest, 1969; Co-Chairman, First International Congress of Immunology, Washington, 1971; Co-Chairman, VII International Congress of Biochemistry, Stockholm, 1973; chairman, Joint Meeting of the European Societies of Immunology, Strasbourg, 1973; Co-Chairman, Second International Congress of Immunology, Brighton, 1974; Co-Chairman, V European Congress of Immunology, Budapest, 1978.
EDITORAL BOARDS:
Studii si Cerectari de Biochimie, 1965-1971; Revue Roumaine de Biochimie, 1965-1971; European Journal of Immunology, 1974-1978; Immunochemistry, 1969-1974; Molecular Immunology, 1980-1987; Journal of Bio-chromatography, 1995; Romanian Society for Immunology, 1971-1979.
B. Selected peer-reviewed publications (in chronological order). Do not include publications submitted or in preparation.
PUBLICATIONS (1998-2002; 214 total):
1. Schnell, R., Vitetta, E.S., Schindler, J., Borchmann, B., Barth, S., Ghetie, V., Hell, K., Drillich, S., Diehl V. and Engert, A. A phase II multicenter trial of bolus infusion of the anti-CD25 ricin A chain immunotoxin RFT5-dgA in patients with refractory Hodgkins lymphoma. Leukemia 14: 129-135, 2000.
2. Messmann, R.A., Vitetta, E.S., Headlee, D., Senderowicz, A.M., Figg, W.D., Schindler, J., Michiel, D.F., Creekmore, S., Steinberg, S.M., Kohler, D., Jaffe, E.S., Stetler-Stevenson, M., Chen, H., Ghetie, V. and Sausville, E.A. A phase I study of combination therapy with immunotoxins IgG-HD37-dgA and IgG-RFB4-dgA (Combotox) in patients with refractory CD19(+), CD22(+) B-cell lymphoma. Clinical Cancer Research, 6:1302-1313, 2000.
3. Baluna, R., Coleman, E., Jones, C., Ghetie, V. and Vitetta, E.S. The effect of a monoclonal antibody coupled to ricin A chain-derived peptides on endothelial cells in vitro: Insights into toxin-mediated vascular damage. Exp. Cell Res. 258: 417-424, 2000.
4. Firan, M., Bawdon, R., Radu, C., Ober, R.J., Eaken, D., Antohe, F., Ghetie, V. and Ward, E.S. The MHC Class I related receptor, FcRn, plays an essential role in the maternofetal transfer of gammaglobulin in humans, Int. Immunol., 13, 993-1002, 2001.
5. Ober, R.J., Radu, C., Ghetie, V. and Ward, E.S. Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies, Int. Immunol., 13, 1551-1559, 2001.
6. Smallshaw, J.E., Firan, A., Fulmer, J.R., Ruback, S.L., Ghetie, V. and Vitetta, E.S. A Novel Recombinant Vaccine which Protects Mice Against Ricin Intoxication. Vaccine, 20:3422-3427, 2002.
7. Herrera, L., Yarbrough, S., Ghetie, V., Aquino, D., and Vitetta, E. Treatment of SCID/Human B-cell precursor ALL with anti-CD19 and anti-CD22 immunotoxins. Leukemia, in press, 2002. |
